Veröffentlichungen

Wissenschaftliche Publikationen

Der wissenschaftliche Hintergrund unserer Arbeit ist in begutachteten Fachzeitschriften dokumentiert. Aufgeführt sind die 60 aktuellsten Arbeiten von Prof. Dr. med. Samer Ezziddin und seinem Team; jeder Eintrag verweist auf den Originaleintrag in PubMed.

  • September 2026

    Organ and tumor dosimetry of [(161)Tb]Tb-PSMA-617 radioligand therapy in patients with mCRPC

    Schaefer-Schuler A, Blickle A, Ganz S, Petto S, Burgard C, Speicher T et al.

    European journal of nuclear medicine and molecular imaging

    Zur Veröffentlichung
  • August 2026

    Diagnosis of Extra-Skeletal Ewing Sarcoma in an 11-Year-Old Child with Large Thoracic Mass revealed by [(18)F]FDG PET/CT

    Rosar F, Bastian MB, Burgard C, Remke M, Collaud S, Kaman H et al.

    Nuclear medicine and molecular imaging

    Zur Veröffentlichung
  • Juli 2026

    Real-world evaluation of [(177)Lu]Lu-PSMA-617 RLT in post-taxane mCRPC: feasibility and safety of individualized treatment in a challenging cohort

    Misirci M, Rosar F, Khreish F, Burgard C, Blickle A, Bartholomä M et al.

    European journal of nuclear medicine and molecular imaging

    Zur Veröffentlichung
  • Juni 2026

    Automated PROMISE V2 Scoring from PSMA PET/CT Reports Using Large Language Models: A Comparative Evaluation of Prompt Design and Model Performance

    Speicher T, Demirkol IE, Blickle A, Bastian MB, Maus S, Schaefer-Schuler A et al.

    Current oncology (Toronto, Ont.)

    Zur Veröffentlichung
  • Juni 2026

    Outcome and Safety of Radioligand Therapy With [ 161 Tb]Tb-PSMA-617 After Re-Progression in mCRPC Patients Previously Treated With [ 177 Lu]Lu-PSMA-617

    Rosar F, Burgard C, Hoang SPT, Blickle A, Bartholomä M, Maus S et al.

    Clinical nuclear medicine

    Zur Veröffentlichung
  • Juli 2026

    Zirconium-89-based PSMA PET/CT with delayed imaging for early detection of biochemical recurrence in prostate cancer patients with PSA ≤ 0.2 ng/mL: A feasibility study

    Speicher T, Latell S, Blickle A, Bastian MB, Maus S, Schaefer-Schuler A et al.

    European journal of nuclear medicine and molecular imaging

    Zur Veröffentlichung
  • Juni 2026

    FDG PET/CT imaging in recurrent papillary thyroid cancer: does BRAF mutation status matter?

    Bastian MB, Kyriakou I, Rosar F, Blickle A, Burgard C, Speicher T et al.

    The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...

    Zur Veröffentlichung
  • März 2026

    Outcome and safety of single-dose docetaxel-augmented targeted radionuclide therapy using [¹⁷⁷Lu]Lu-PSMA-617 radioligand therapy in treatment-refractory mCRPC: preliminary evidence from a pilot experience

    Ebert N, Rosar F, Burgard C, Bartholomä M, Maus S, Hein C et al.

    EJNMMI research

    Zur Veröffentlichung
  • Februar 2026

    Dosimetric analysis reveals rapid clearance and low absorbed dose of [¹⁷⁷Lu]Lu-PSMA-617 in non-prostate cancers with high PSMA expression

    Khreish F, Rosar F, Burgard C, Petto S, Maus S, Stemler T et al.

    EJNMMI research

    Zur Veröffentlichung
  • Februar 2026

    Auger Emitting [(161)Tb]Tb-PSMA-617 Radioligand Therapy in mCRPC with Peritoneal Carcinomatosis

    Rosar F, Blickle A, Bastian MB, Speicher T, Schaefer-Schuler A, Burgard C et al.

    Nuclear medicine and molecular imaging

    Zur Veröffentlichung
  • April 2026

    Comparison of mCRPC [(177)Lu]Lu-PSMA-617 radioligand therapy with and without concurrent enzalutamide medication in a real-world setting

    Rosar F, Khreish F, Burgard C, Fursov A, Blickle A, Bartholomä M et al.

    European journal of nuclear medicine and molecular imaging

    Zur Veröffentlichung
  • 2025

    Advancing patient education in PRRT through large language models: challenges and potential

    Speicher T, Bastian MB, Blickle A, Atzinger A, Rosar F, Burgard C et al.

    American journal of nuclear medicine and molecular imaging

    Zur Veröffentlichung
  • 2025

    Pilot experience of [(161)Tb]Tb-PSMA-617 RLT in mCRPC patients after conventional PSMA RLT within a prospective registry

    Rosar F, Burgard C, Petrescu C, Blickle A, Bartholomä M, Maus S et al.

    Theranostics

    Zur Veröffentlichung
  • Dezember 2025

    Assessment of scintigraphic imaging with Terbium-161: A visual and quantitative analysis

    Rosar F, Petto S, Ganz S, Burgard C, Maus S, Bartholomä M et al.

    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

    Zur Veröffentlichung
  • Juli 2025

    Tolerability of PSMA radioligand therapy in metastatic prostate cancer patients with baseline mild to moderate leukopenia

    Bastian MB, Speicher T, Blickle A, Burgard C, Bastian JLD, Bartholomä M et al.

    EJNMMI research

    Zur Veröffentlichung
  • Juni 2025

    Tumor sink effect in PSMA-targeted theranostics: intra-patient evaluation of a cohort receiving 225Ac/177Lu-PSMA tandem radioligand therapy

    Burgard C, Muenzenberg MD, Blickle A, Bartholomä M, Maus S, Petto S et al.

    The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...

    Zur Veröffentlichung
  • März 2026

    Novel 64 Cu-labeled Trimeric PSMA Ligand Unequivocally Identifies Local Recurrence of Prostate Cancer Ambiguously Imaged by 18 F-DCFPyL PSMA PET/CT

    Bartholomä M, Rosar F, Burgard C, Maus S, Schreck MV, Ezziddin S

    Clinical nuclear medicine

    Zur Veröffentlichung
  • Juli 2025

    Radiochemistry of cyclen-derived chelators comprising five-membered azaheterocyclic arms with (212)Pb(2+), (213)Bi(3+), and (225)Ac(3)

    Hierlmeier I, Randhawa P, McNeil BL, Oliveri E, Maus S, Radchenko V et al.

    Nuclear medicine and biology

    Zur Veröffentlichung
  • November 2025

    Expanding the scope of PSMA-RLT: evaluating treatment in challenging mCRPC patients with poor performance status (ECOG 3)

    Bastian MB, Wörl B, Blickle A, Burgard C, Speicher T, Bartholomä M et al.

    European journal of nuclear medicine and molecular imaging

    Zur Veröffentlichung
  • September 2025

    PSMA Radioligand Therapy in Advanced Age: Insights From an 85y+ mCRPC Patient Cohort

    Bastian MB, Wörl B, Blickle A, Burgard C, Speicher T, Wessendorf J et al.

    Clinical nuclear medicine

    Zur Veröffentlichung
  • Oktober 2025

    PSMA PET/CT in biochemical recurrence of prostate cancer with PSA levels ≤ 0.2 ng/mL: a German multicenter analysis of conventional PSMA tracers, including [(68)Ga]Ga-PSMA-11, [(68)Ga]Ga-PSMA I&T, and [(18)F]PSMA-1007

    Burgard C, Frei M, Blickle A, Hartrampf PE, Hoffmann MA, Schreckenberger M et al.

    European journal of nuclear medicine and molecular imaging

    Zur Veröffentlichung
  • Oktober 2025

    Superior Response of CAP-PRRT of G3 NET When Switching to the Somatostatin Receptor Antagonist LM3: Intraindividual Proof-of-concept

    Speicher T, Burgard C, Rosar F, Bastian M, Bartholomä M, Maus S et al.

    Clinical nuclear medicine

    Zur Veröffentlichung
  • Januar 2026

    Superior NET Targeting by Switch From Agonist to Antagonist-mediated Somatostatin Receptor Theranostics Allowing Successful (LM3-based) PRRT of Otherwise Precluded mNET: Intraindividual Proof-of-concept

    Speicher T, Burgard C, Rosar F, Bastian M, Bartholomä M, Maus S et al.

    Clinical nuclear medicine

    Zur Veröffentlichung
  • März 2025

    [(18)F]FDG PET/CT of Langerhans Cell Histiocytosis with Vertebra Plana

    Speicher T, Bastian MB, Christofyllakis K, Rosar F, Ezziddin S, Burgard C

    Diagnostics (Basel, Switzerland)

    Zur Veröffentlichung
  • Oktober 2025

    [(68)Ga]Ga-FAPI-04 PET/CT in a patient with endometriosis: a potential game changer?

    Burgard C, Rosar F, Ezziddin S, Hamoud BH, Solomayer EF, Laschke MW et al.

    European journal of nuclear medicine and molecular imaging

    Zur Veröffentlichung
  • 2025

    Prediction of lesion-based response to PRRT using baseline somatostatin receptor PET

    Aouf A, Speicher T, Blickle A, Bastian MB, Burgard C, Rosar F et al.

    Frontiers in medicine

    Zur Veröffentlichung
  • August 2025

    Early changes of PSMA PET expression after initiation of androgen receptor signaling inhibitors in CRPC: an international multicenter retrospective study

    Unterrainer LM, Farolfi A, Grogan T, Hotta M, Djaileb L, Gafita A et al.

    European journal of nuclear medicine and molecular imaging

    Zur Veröffentlichung
  • April 2025

    225 Ac-PSMA-617 Augmentation After Insufficient Response Under 177 Lu-PSMA-617 Radioligand Therapy in mCRPC: Evaluation of Outcome and Safety From a Prospective Registry (REALITY Study)

    Rosar F, Khreish F, Nagel LS, Blickle A, Burgard C, Petto S et al.

    Clinical nuclear medicine

    Zur Veröffentlichung
  • Februar 2025

    Diffuse Peritoneal Carcinomatosis of Prostate Cancer Unveiled by [89Zr]Zr-PSMA-617 PET/CT

    Bastian MB, Burgard C, Blickle A, Ezziddin S, Rosar F

    Clinical nuclear medicine

    Zur Veröffentlichung
  • Dezember 2024

    Development of a homotrimeric PSMA radioligand based on the NOTI chelating platform

    Martin S, Schreck MV, Stemler T, Maus S, Rosar F, Burgard C et al.

    EJNMMI radiopharmacy and chemistry

    Zur Veröffentlichung
  • Januar 2025

    First Successful In-Human Application of 225Ac-DOTA-LM3 Mono-PRRT for the Treatment of an Otherwise Therapy-Resistant Neuroendocrine Tumor (NET G3)

    Speicher T, Burgard C, Bastian M, Rosar F, Bartholomä M, Maus S et al.

    Clinical nuclear medicine

    Zur Veröffentlichung
  • März 2025

    Safety of PSMA radioligand therapy in mCRPC patients with preexisting moderate to severe thrombocytopenia

    Bastian MB, Sieben M, Blickle A, Burgard C, Speicher T, Bartholomä M et al.

    European journal of nuclear medicine and molecular imaging

    Zur Veröffentlichung
  • Februar 2025

    Outcome and Renal Safety of PSMA-Targeted Radioligand Therapy in mCRPC Patients With Preexisting Impaired Renal Function

    Bastian MB, Sieben M, Burgard C, Blickle A, Speicher T, Bartholomä M et al.

    Clinical nuclear medicine

    Zur Veröffentlichung
  • Oktober 2024

    Analysis of Molecular Imaging Biomarkers Derived from [(18)F]FDG PET/CT in mCRPC: Whole-Body Total Lesion Glycolysis (TLG) Predicts Overall Survival in Patients Undergoing [(225)Ac]Ac-PSMA-617-Augmented [(177)Lu]Lu-PSMA-617 Radioligand Therapy

    Burgard C, Khreish F, Dahlmanns L, Blickle A, Bastian MB, Speicher T et al.

    Cancers

    Zur Veröffentlichung
  • Oktober 2024

    [(89)Zr]Zr-PSMA-617 PET/CT in a Patient with Biochemical Recurrence of Prostate Cancer and Prior Indetermined Findings on [(18)F]PSMA-1007 Imaging

    Bastian MB, Burgard C, Blickle A, Speicher T, Ezziddin S, Rosar F

    Diagnostics (Basel, Switzerland)

    Zur Veröffentlichung
  • Oktober 2024

    Outstanding increase in tumor-to-background ratio over time allows tumor localization by [(89)Zr]Zr-PSMA-617 PET/CT in early biochemical recurrence of prostate cancer

    Burgard C, Rosar F, Larsen E, Khreish F, Linxweiler J, Marlowe RJ et al.

    Cancer imaging : the official publication of the International Cancer Imaging Society

    Zur Veröffentlichung
  • Oktober 2024

    Radiochemistry and Complex Formation of the Cyclen-Derived Chelator DOTI-Me with Mn(2+), Cu(2+), Zn(2+), Ga(3+), In(3+), Tb(3+), and Lu(3)

    Hierlmeier I, Marino N, Schreck MV, Schneider L, Maus S, Barrett K et al.

    Inorganic chemistry

    Zur Veröffentlichung
  • November 2024

    Ectopic Cushing Syndrome Localized by 68 Ga-DOTA-LM3 PET/CT

    Bastian MB, Rosar F, Burgard C, Blickle A, Ezziddin S

    Clinical nuclear medicine

    Zur Veröffentlichung
  • Juli 2024

    Analysis of Molecular Imaging and Laboratory Baseline Biomarkers in PSMA-RLT: Whole-Body Total Lesion PSMA (TLP) Predicts Overall Survival

    Hein C, Burgard C, Blickle A, Bastian MB, Maus S, Schaefer-Schuler A et al.

    Cancers

    Zur Veröffentlichung
  • November 2024

    Efficacy and safety of rechallenge [(177)Lu]Lu-PSMA-617 RLT after initial partial remission in patients with mCRPC: evaluation of a prospective registry (REALITY study)

    Rosar F, Schuler J, Burgard C, Blickle A, Bartholomä M, Maus S et al.

    European journal of nuclear medicine and molecular imaging

    Zur Veröffentlichung
  • Mai 2024

    Histopathological Confirmed Polycythemia Vera with Transformation to Myelofibrosis Depicted on [(18)F]FDG PET/CT

    Bastian MB, Blickle A, Burgard C, Fleser O, Christofyllakis K, Ezziddin S et al.

    Diagnostics (Basel, Switzerland)

    Zur Veröffentlichung
  • Juli 2024

    225 Ac-PSMA-617 Augmentation in High-Risk mCRPC Undergoing 177 Lu-PSMA-617 Radioligand Therapy : Pilot Experience From a Prospective Registry

    Rosar F, Burgard C, Rohloff LV, Blickle A, Bartholomä M, Maus S et al.

    Clinical nuclear medicine

    Zur Veröffentlichung
  • Mai 2024

    Dual FDG/PSMA PET imaging to predict lesion-based progression of mCRPC during PSMA-RLT

    Rosar F, Burgard C, David S, Marlowe RJ, Bartholomä M, Maus S et al.

    Scientific reports

    Zur Veröffentlichung
  • April 2024

    Mind the Pitfall: Solitary Nodular Fasciitis Mimicking Extra-Nodal Manifestation of Hodgkin Lymphoma on [(18)F]FDG PET/CT

    Markandu S, Blickle A, Burgard C, Remke M, Altmeyer K, Wagner M et al.

    Diagnostics (Basel, Switzerland)

    Zur Veröffentlichung
  • 2024

    Concomitant lithium increases radioiodine uptake and absorbed doses per administered activity in graves' disease: comparison of conventional versus lithium-augmented radioiodine therapy

    Khreish F, Schaefer-Schuler A, Roth L, Burgard C, Rosar F, Ezziddin S

    Frontiers in medicine

    Zur Veröffentlichung
  • 2024

    [(161)Tb]Tb-PSMA-617 radioligand therapy in patients with mCRPC: preliminary dosimetry results and intra-individual head-to-head comparison to [(177)Lu]Lu-PSMA-617

    Schaefer-Schuler A, Burgard C, Blickle A, Maus S, Petrescu C, Petto S et al.

    Theranostics

    Zur Veröffentlichung
  • Mai 2024

    Mast Cell Sarcoma Mimicking Lymphoma or Metastatic Disease on 18 F-FDG PET/CT

    Rosar F, Ezziddin S, Bittenbring JT, Christofyllakis K, Burgard C

    Clinical nuclear medicine

    Zur Veröffentlichung
  • Februar 2024

    [(89)Zr]Zr-PSMA-617 PET/CT characterization of indeterminate [(68)Ga]Ga-PSMA-11 PET/CT findings in patients with biochemical recurrence of prostate cancer: lesion-based analysis

    Rosar F, Burgard C, Larsen E, Khreish F, Marlowe RJ, Schaefer-Schuler A et al.

    Cancer imaging : the official publication of the International Cancer Imaging Society

    Zur Veröffentlichung
  • 2023

    Change of glucometabolic activity per PSMA expression predicts survival in mCRPC patients non-responding to PSMA radioligand therapy: introducing a novel dual imaging biomarker

    Burgard C, Engler J, Blickle A, Bartholomä M, Maus S, Schaefer-Schuler A et al.

    Frontiers in medicine

    Zur Veröffentlichung
  • Januar 2024

    Safety and Efficacy of Selective Internal Radionuclide Therapy with (90)Y Glass Microspheres in Patients with Progressive Hepatocellular Carcinoma after the Failure of Repeated Transarterial Chemoembolization

    Bellendorf A, Mader N, Mueller SP, Ezziddin S, Bockisch A, Grafe H et al.

    Pharmaceuticals (Basel, Switzerland)

    Zur Veröffentlichung
  • Dezember 2023

    Active Lumbar Spondylodiscitis on [(68)Ga]Ga-PSMA-11 PET/CT Mimicking Bone Metastasis

    Rosar F, Burgard C, Gargiulo R, Ezziddin S

    Diagnostics (Basel, Switzerland)

    Zur Veröffentlichung
  • Dezember 2023

    Radiometal Complexes as Pharmacokinetic Modifiers: A Potent (68)Ga-Labeled Gastrin-Releasing Peptide Receptor Antagonist Based on the Macrocyclic Metal Chelator NODIA-Me

    Schreck MV, Burgard C, Schmidtke A, Hierlmeier I, Stemler T, Maus S et al.

    Molecular pharmaceutics

    Zur Veröffentlichung
  • Februar 2024

    Change in total lesion PSMA (TLP) during [(177)Lu]Lu-PSMA-617 radioligand therapy predicts overall survival in patients with mCRPC: monocentric evaluation of a prospective registry

    Burgard C, Hein C, Blickle A, Bartholomä M, Maus S, Petto S et al.

    European journal of nuclear medicine and molecular imaging

    Zur Veröffentlichung
  • Juli 2023

    Joint EANM/SNMMI procedure guideline for the use of (177)Lu-labeled PSMA-targeted radioligand-therapy ((177)Lu-PSMA-RLT)

    Kratochwil C, Fendler WP, Eiber M, Hofman MS, Emmett L, Calais J et al.

    European journal of nuclear medicine and molecular imaging

    Zur Veröffentlichung
  • Mai 2023

    Tumor Sink Effect with Prostate-Specific Membrane Antigen-Targeted Theranostics in Patients with Metastatic Castration-Resistant Prostate Cancer: Intra-Individual Evaluations

    Burgard C, Rosar F, Marlowe RJ, Bartholomä M, Dewes S, Schaefer-Schuler A et al.

    Cancers

    Zur Veröffentlichung
  • Juli 2023

    Detection efficacy of [(89)Zr]Zr-PSMA-617 PET/CT in [(68)Ga]Ga-PSMA-11 PET/CT-negative biochemical recurrence of prostate cancer

    Rosar F, Khreish F, Marlowe RJ, Schaefer-Schuler A, Burgard C, Maus S et al.

    European journal of nuclear medicine and molecular imaging

    Zur Veröffentlichung
  • April 2023

    Histologically Confirmed Testicular Metastasis Revealed by [(89)Zr]Zr-PSMA-617 PET/CT in a Patient with Biochemical Recurrence of Prostate Cancer and Negative Conventional PSMA PET/CT Imaging

    Rosar F, Burgard C, Linxweiler J, Wagner M, Ezziddin S

    Diagnostics (Basel, Switzerland)

    Zur Veröffentlichung
  • Februar 2023

    Detection Efficacy of (68)Ga-PSMA-11 PET/CT in Biochemical Recurrence of Prostate Cancer with Very Low PSA Levels: A 7-Year, Two-Center "Real-World" Experience

    Burgard C, Hoffmann MA, Frei M, Buchholz HG, Khreish F, Marlowe RJ et al.

    Cancers

    Zur Veröffentlichung
  • Mai 2023

    New Horizons in Radioligand Therapy: 161Tb-PSMA-617 in Advanced mCRPC

    Rosar F, Maus S, Schaefer-Schuler A, Burgard C, Khreish F, Ezziddin S

    Clinical nuclear medicine

    Zur Veröffentlichung
  • Dezember 2022

    PSMA-RLT in Patients with Metastatic Hormone-Sensitive Prostate Cancer: A Retrospective Study

    Banda A, Privé BM, Allach Y, Uijen MJM, Peters SMB, Loeff CC et al.

    Cancers

    Zur Veröffentlichung